Synthesis and Cytotoxicity of Chalcone Based 1,2,3-Triazole Derivatives

Synthesis of a novel series of chalcone based 1,2,3-triazole derivatives and their anti-cancer studies are presented. Majority of the target compounds exhibit moderate to excellent activity against A-549 cells. Among the compounds screened 7c and 7j demonstrate potent activity being compared with the standard drug Doxorubicin.