Nuclear Mechanics: Nuclear Mechanics within Intact Cells Is Regulated by Cytoskeletal Network and Internal Nanostructures (Small 18/2020)

Nuclear Mechanics: Nuclear Mechanics within Intact Cells Is Regulated by Cytoskeletal Network and Internal Nanostructures (Small 18/2020)

In article number 1907688, Vivek B. Shenoy, Giuliano Scarcelli, and co‐workers use all‐optical Brillouin microscopy and 3D chemomechanical modeling to investigate the regulation of nuclear mechanics. It is observed that the nuclear modulus can be modulated by both epigenetic regulation targeting int...

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Veröffentlicht in:Small (Weinheim an der Bergstrasse, Germany) Germany), 2020-05, Vol.16 (18), p.n/a
Hauptverfasser: Zhang, Jitao, Alisafaei, Farid, Nikolić, Miloš, Nou, Xuefei A., Kim, Hanyoup, Shenoy, Vivek B., Scarcelli, Giuliano
Format: Artikel
Sprache:eng
Schlagworte:
Brillouin microscopy
chemomechanical modeling
cytoskeletal network
Mechanics
Mechanics (physics)
Nanostructure
nanostructures
Nanotechnology
nuclear mechanics
Three dimensional models
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Zusammenfassung:In article number 1907688, Vivek B. Shenoy, Giuliano Scarcelli, and co‐workers use all‐optical Brillouin microscopy and 3D chemomechanical modeling to investigate the regulation of nuclear mechanics. It is observed that the nuclear modulus can be modulated by both epigenetic regulation targeting internal nanostructures and cytoskeletal behavior through a robust mechanism conserved in different culturing conditions.
ISSN:1613-6810
1613-6829
DOI:10.1002/smll.202070098