Outcome and risk of ocular complications of managing children with chronic anterior uveitis with topical rimexolone 1

Purpose To investigate the efficacy and safety of 1% rimexolone ophthalmic suspension in children with chronic anterior uveitis under real-life conditions in a tertiary center. Methods This is a retrospective longitudinal study. Medical records were analyzed at baseline, 1, 3, 6 and 12 months before...

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Veröffentlicht in:International ophthalmology 2020-05, Vol.40 (5), p.1061-1068
Hauptverfasser: Chen, Yi-Hsing, Gepstein, Raz, Sharief, Lazha, Tseng, Hsiao-Jung, Wei, Ruoxin, Zhang, Xiaozhe, Lightman, Sue, Tomkins-Netzer, Oren
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Sprache:eng
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Zusammenfassung:Purpose To investigate the efficacy and safety of 1% rimexolone ophthalmic suspension in children with chronic anterior uveitis under real-life conditions in a tertiary center. Methods This is a retrospective longitudinal study. Medical records were analyzed at baseline, 1, 3, 6 and 12 months before and after switching to rimexolone for best-corrected visual acuity (BCVA), oral steroid use, number of flares, IOP and anti-glaucoma management. Results Twenty-four patients (41 eyes) diagnosed with either anterior uveitis ( n  = 25, 60.0%) or panuveitis ( n  = 16, 40%) were enrolled. The mean age was 10.5 years (4–16 years). The number of patients requiring oral prednisolone reduced from 8 patients (32.0%) at baseline to 3 patients (20.0%) at 12 months ( P  
ISSN:0165-5701
1573-2630
DOI:10.1007/s10792-020-01358-9