Vitamin K1 Treatment Duration in Patients with Brodifacoum Poisoning

Vitamin K1 Treatment Duration in Patients with Brodifacoum Poisoning

The rodenticide brodifacoum, a long-acting vitamin K epoxide cycle antagonist, can produce life-threatening hemorrhage in exposed humans. Its toxic effects are treated with vitamin K 1 , but monitoring such therapy is difficult. The authors of this letter advocate monitoring brodifacoum levels with...

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Veröffentlicht in:The New England journal of medicine 2020-04, Vol.382 (18), p.1764-1765
Hauptverfasser: Yip, Luke, Stanton, Noel V, Middleberg, Robert A
Format: Artikel
Sprache:eng
Schlagworte:
Hemorrhage
Laboratories
Poisoning
Rodenticides
Vitamin K
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Zusammenfassung:The rodenticide brodifacoum, a long-acting vitamin K epoxide cycle antagonist, can produce life-threatening hemorrhage in exposed humans. Its toxic effects are treated with vitamin K 1 , but monitoring such therapy is difficult. The authors of this letter advocate monitoring brodifacoum levels with newly available assays.
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMc1916199