Using a Stationary Phase Based on Porous Graphitized Carbon for the Determination of 1,1-Dimethylhydrazine Transformation Products by Liquid Chromatography–Mass Spectrometry

An approach to the simultaneous determination of five products of the transformation of rocket fuel on the basis of 1,1-dimethylhydrazine (1-methyl-1H-1,2,4-triazole, N -nitrosodimethylamine, N , N -dimethylformamide, and formaldehyde and acetaldehyde dimethylhydrazones) is proposed based on a combi...

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Veröffentlicht in:Journal of analytical chemistry (New York, N.Y.) N.Y.), 2020-04, Vol.75 (4), p.510-518
Hauptverfasser: Ul’yanovskii, N. V., Kosyakov, D. S., Popov, M. S., Pikovskoi, I. I., Khoroshev, O. Yu
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Sprache:eng
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Zusammenfassung:An approach to the simultaneous determination of five products of the transformation of rocket fuel on the basis of 1,1-dimethylhydrazine (1-methyl-1H-1,2,4-triazole, N -nitrosodimethylamine, N , N -dimethylformamide, and formaldehyde and acetaldehyde dimethylhydrazones) is proposed based on a combination HPLC on porous graphitized carbon (Hypercarb) with mass spectrometry and tandem mass spectrometry detection. The limits of detection are 0.6–7 µg/L. It was found that the stationary phase based on porous graphitized carbon ensures the effective chromatographic retention and separation of nitrogen-containing products 1,1-dimethylhydrazine transformation products by a mixed mechanism, including both hydrophobic and induction interactions with the analytes. The absence of matrix effects in the analysis of natural waters and a methanol extract from peat bog soil was shown.
ISSN:1061-9348
1608-3199
DOI:10.1134/S1061934820040140