A label-free homogeneous electrochemical cytosensor for the ultrasensitive detection of cancer cells based on multiaptamer-functionalized DNA tetrahedral nanostructures

We developed a label-free homogeneous electrochemical cytosensor for ultrasensitive detection of cancer cells based on multiaptamer-functionalized DNA tetrahedral nanostructures, which avoided expensive labeling and sophisticated immobilization procedures, providing opportunities for precisely detec...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2020-04, Vol.56 (27), p.3883-3886
Hauptverfasser: Yang, Limin, Yin, Xuehan, Gai, Panpan, Li, Feng
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Sprache:eng
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Zusammenfassung:We developed a label-free homogeneous electrochemical cytosensor for ultrasensitive detection of cancer cells based on multiaptamer-functionalized DNA tetrahedral nanostructures, which avoided expensive labeling and sophisticated immobilization procedures, providing opportunities for precisely detecting cancer cells in clinical applications. A label-free homogeneous electrochemical cytosensor was developed for ultrasensitive detection of cancer cells based on multiaptamer-functionalized DNA tetrahedral nanostructures.
ISSN:1359-7345
1364-548X
DOI:10.1039/d0cc00788a