Chemical Composition, Antibacterial, Anti-oxidant and Cytotoxic properties of Green Synthesized Silver Nanoparticles from Annona muricata L. (Annonaceae)

The morphological changes, membrane damage, cell shrinkage and cell death were evidenced by MTT assay, AO/EB staining and DNA fragmentation. [...]the AgNPs showed excellent results than aqueous extract in all the biological activities. Among them, chemical method contains an enormous side effect to environment due to the usage of toxic chemicals having more expensive. [...]green chemistry attained more attention in nanotechnology field and so the synthesis and characterization of nanomaterials through green and ecofriendly approach is an emerging area in nanotechnology from last few decades. [...]the researchers started synthesis of AgNPs from several plant leaf extracts Nelumbonucifera14, Ecliptaprostrata15, O. thymiflorus16 and Saracaindica etc.,17 respectively. Due to several health threats in widely used synthetic antioxidants like BHA, warfarin and BHT were under strict regulation20. [...]the natural resources were used to derive antioxidants from various plants namely Melothriamaderaspatana21, Brassica nigra22, Lantana camara etc.,23 due to non-toxic and control ROS with the help of their medicinal components24.