Formulation and Characterization of Resorcinol Peel

The glands produce oil which are stimulated by male hormones produced by the adrenal glands in both males and females. Once considered to be a disease of the apocrine glands, it is actually a defect of follicular epithelium. [...]the term hidradenitissuppurativa is a misnomer and should be abandoned. (13)(38)(39) Method of Preparation(10)(15): 1 Calculate the required quantity of each ingredient for the total amount to be prepared. 2 Accurately weigh/measure each ingredient. 3 Dissolve the resorcinol in the purified water. 4 Dissolve the salicylic acid in the alcohol, followed by the lactic acid and mix well. 5 Add the two solutions together. 6 Add sufficient purified water to volume and mix well. 7 Package in an amber container and label. (15)(37)(41) How to apply:(16)(35) Peeling Technique * The skin is scrubbed with alcoholor acetone * The gel is spread over the face. * Start on forehead and Continue on the cheeks * Then the nose and the chin up to 1 cm below the mandibular margin * The patient is instructed to keep the eyes and the mouth closed to prevent accidents pillage * The gel is kept for 15-20minutes. * The paste is removed with water. * After the removal of the paste the skin is white but turns to pink within 2 to 3 h. Advantages:(17)(33)(34) * Easy to perform * Uniformity of application and penetration * Effective especially in acne, post-inflammatory hyperpigmentation and melasma * Not painful (the burning sensation during the peeling is usually mild) Characterization: After getting best formulae based on resorcinol, salicylic acid and lactic acid ratio, it was further studied for its characterization such as pH value, viscosity, physical appearance, homogeneity, spreadabibility, grittiness, etc.