Preparation of novel azidopyrazole derivatives with anticipated cytotoxic and antimicrobial activities

Preparation of novel azidopyrazole derivatives with anticipated cytotoxic and antimicrobial activities

The reactions of azidopyrazole with some of primary amines and active methylene compounds were studied. Structures of the prepared compounds were identified using spectroscopic techniques. The reactions mechanisms were also proposed. The cytotoxic and antimicrobial activities were also examined for...

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Veröffentlicht in:Journal of heterocyclic chemistry 2020-03, Vol.57 (3), p.965-977
Hauptverfasser: Ewies, Ewies F., El‐Hussieny, Marwa, El‐Sayed, Naglaa F., El‐Shazly, Mohamed, Chen, Yu‐Cheng, Liu, Yi‐Chang
Format: Artikel
Sprache:eng
Schlagworte:
Amines
Antiinfectives and antibacterials
Cytotoxicity
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Zusammenfassung:The reactions of azidopyrazole with some of primary amines and active methylene compounds were studied. Structures of the prepared compounds were identified using spectroscopic techniques. The reactions mechanisms were also proposed. The cytotoxic and antimicrobial activities were also examined for the newly synthesized compounds.
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.3747