A New 26-Norlanostanoid from the Fruiting Bodies of Ganoderma philippii

A New 26-Norlanostanoid from the Fruiting Bodies of Ganoderma philippii

A new nortriterpenoid, 26-nor-11,22-dioxolanost-8-en-3β,7β,15α-triol ( 1 ), was isolated from the EtOAc extract of the fruiting bodies of Ganoderma philippii. Its structure was identified by spectroscopic techniques including 1D and 2D spectral data as well as MS. Compound 1 showed α-glucosidase inh...

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Veröffentlicht in:Chemistry of natural compounds 2020, Vol.56 (1), p.89-91
Hauptverfasser: Ma, Qing-Yun, Yang, Shuang, Kong, Fan-Dong, Xie, Qing-Yi, Zhou, Li-Man, Yu, Zhi-Fang, Zhao, You-Xing
Format: Artikel
Sprache:eng
Schlagworte:
Glucosidase
Medicine
Organic Chemistry
Pharmacy
Plant Sciences
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Zusammenfassung:A new nortriterpenoid, 26-nor-11,22-dioxolanost-8-en-3β,7β,15α-triol ( 1 ), was isolated from the EtOAc extract of the fruiting bodies of Ganoderma philippii. Its structure was identified by spectroscopic techniques including 1D and 2D spectral data as well as MS. Compound 1 showed α-glucosidase inhibitory activity with IC 50 value of 482.7 μM.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-020-02950-2