A New Flavonoid Glycoside with α-Glucosidase Inhibitory Activity from Galium Verum

A New Flavonoid Glycoside with α-Glucosidase Inhibitory Activity from Galium Verum

A new flavonoid glycoside, apigenin 7-O-(2,4-di-O-acetyl)-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside ( 1 ), was isolated from the 95% EtOH extract of Galium verum L. by repeated column chromatography. Its structure was identified by spectral analyses and chemical methods. In addition, the rat int...

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Veröffentlicht in:Chemistry of natural compounds 2020, Vol.56 (1), p.67-69
Hauptverfasser: Zhang, Xiao-Hui, Shen, Jie, Zhao, Chun-Chao, Shao, Jian-Hua
Format: Artikel
Sprache:eng
Schlagworte:
Column chromatography
Columnar structure
Flavone glycosides
Flavonoids
Glucosidase
Identification methods
Medicine
Organic Chemistry
Pharmacy
Plant Sciences
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Zusammenfassung:A new flavonoid glycoside, apigenin 7-O-(2,4-di-O-acetyl)-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside ( 1 ), was isolated from the 95% EtOH extract of Galium verum L. by repeated column chromatography. Its structure was identified by spectral analyses and chemical methods. In addition, the rat intestinal α-glucosidase inhibitory activity of compound 1 was evaluated in vitro.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-020-02945-z