0269 Evaluation of Sleep in a Birth Cohort Study: Initial Results

Introduction Sleep disorders are very prevalent. The most common conditions are: insomnia, obstructive sleep apnea (OSA), excessive sleepiness and Willis-Ekbom's Disease (DWE). Studies of birth cohorts bring the possibility of conducting research with a temporal window that begins at birth and extends to the present, representing a unique opportunity to understand the possible mechanisms that lead to sleep-related disorders. In these initial findings, our objective was to evaluate sleep quality, excessive sleepiness, OSA risk and DWE prevalence. Methods In this initial analysis of the study we carried out a transversal evaluation of the individuals born in 1978 and 1994 in the city of Ribeirão Preto (Brazil). This population is being followed longitudinally from birth. In 2017, they were reevaluated for the following outcomes: OSA risk (STOP-BANG questionnaire), sleep quality (Pittsburgh Sleep Quality Index), excessive drowsiness (Epworth Sleepiness Scale), and DWE prevalence with a one question. Results Were included in this phase of the study 1773 individuals born in 1978 and 1041 individuals born in 1994. Of those born in 1978, 846 were males and 929 females. Of the total, 30.45% presented high risk of OSA and 64.58% had low risk. Sleep quality was poor for 58.54%, and 32.14% presented excessive sleepiness. Regarding DWE, 113 (6.37%) reported symptoms, being more common in females. Of the individuals born in 1994, 436 were males and 605 females. Of the total, 14.60% presented high risk of OSA and 67.33 low risk. Sleep quality was poor for 57.82%, and 36.21% presented excessive sleepiness. Sixty-one (5.8%) reported DWE symptoms, being more common in females. Conclusion The sleep-related disorders are very prevalent in individuals between the ages of 38 and 39 years and 22 and 23 years old in the city of Ribeirão Preto. Support (If Any) This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES) - Finance Code 001.