1009 Predictors of Improved Pain Interference with Sleep in a Real-World Chronic Pain Cohort by Transcutaneous Electrical Nerve Stimulation

Introduction Fixed-site high-frequency TENS (FS-TENS) is a form of TENS in which the stimulator is designed for a predetermined location rather than for co-localization with the patient’s pain. A single target site enables design of small wearable devices that may be used while active and sleeping....

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Veröffentlicht in:Sleep (New York, N.Y.) N.Y.), 2019-04, Vol.42 (Supplement_1), p.A406-A406
Hauptverfasser: Gozani, Shai, Kong, Xuan, Ferree, Thomas
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Sprache:eng
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Zusammenfassung:Introduction Fixed-site high-frequency TENS (FS-TENS) is a form of TENS in which the stimulator is designed for a predetermined location rather than for co-localization with the patient’s pain. A single target site enables design of small wearable devices that may be used while active and sleeping. Previous studies demonstrated that FS-TENS reduces pain interference with sleep (“sleep interference”) in chronic lower extremity or low back pain. The objective of this study was to determine predictors of reduced sleep interference in individuals self-administering FS-TENS. Methods This retrospective cohort study evaluated real-world use of a FS-TENS device (Quell®, NeuroMetrix, Waltham MA), placed on the upper calf, for chronic pain over 10-weeks. The device and companion smartphone app collect TENS utilization (%days with at least 30 minutes stimulation), demographics, pain characteristics and pain ratings that are stored in a cloud database. The study outcome was the baseline to 10-week change in sleep interference (11-point NRS). Participants were defined as a responder (≥1-point decrease) or comparator (≥1-point increase) based on their change in sleep interference. Stepwise forward probit regression was used to determine independent predictors. Classification accuracy was assessed by the area under the ROC curve. Results There were 889 responders and 759 comparators. The most common chronic pain conditions were arthritis, prior back injury and herniated disc. Responders were slightly older (57±13 vs 56±14, p
ISSN:0161-8105
1550-9109
DOI:10.1093/sleep/zsz067.1006