Synthesis of Amphiphilic Peptidomimetics Based on the Aliphatic Derivatives of Natural Amino Acids

—The paper describes the production of a number of lipoamino acid derivatives based on L-serine, L-ornithine, and L-lysine with potential antibacterial activity. The designed synthesis schemes are distinguished by the simplicity and versatility of the approach used. This allows us to use them to obt...

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Veröffentlicht in:Moscow University chemistry bulletin 2019-11, Vol.74 (6), p.300-305
Hauptverfasser: Denieva, Z. G., Romanova, N. A., Bodrova, T. G., Budanova, U. A., Sebyakin, Yu. L.
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container_end_page 305
container_issue 6
container_start_page 300
container_title Moscow University chemistry bulletin
container_volume 74
creator Denieva, Z. G.
Romanova, N. A.
Bodrova, T. G.
Budanova, U. A.
Sebyakin, Yu. L.
description —The paper describes the production of a number of lipoamino acid derivatives based on L-serine, L-ornithine, and L-lysine with potential antibacterial activity. The designed synthesis schemes are distinguished by the simplicity and versatility of the approach used. This allows us to use them to obtain a series of samples in preparative quantities required to perform the subsequent physico-chemical and biochemical studies.
doi_str_mv 10.3103/S0027131419060087
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subjects Aliphatic compounds
Amino acids
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Derivatives
Lysine
Organic chemistry
Synthesis
title Synthesis of Amphiphilic Peptidomimetics Based on the Aliphatic Derivatives of Natural Amino Acids
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