Synthesis of Amphiphilic Peptidomimetics Based on the Aliphatic Derivatives of Natural Amino Acids

—The paper describes the production of a number of lipoamino acid derivatives based on L-serine, L-ornithine, and L-lysine with potential antibacterial activity. The designed synthesis schemes are distinguished by the simplicity and versatility of the approach used. This allows us to use them to obt...

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Veröffentlicht in:Moscow University chemistry bulletin 2019-11, Vol.74 (6), p.300-305
Hauptverfasser: Denieva, Z. G., Romanova, N. A., Bodrova, T. G., Budanova, U. A., Sebyakin, Yu. L.
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Sprache:eng
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Zusammenfassung:—The paper describes the production of a number of lipoamino acid derivatives based on L-serine, L-ornithine, and L-lysine with potential antibacterial activity. The designed synthesis schemes are distinguished by the simplicity and versatility of the approach used. This allows us to use them to obtain a series of samples in preparative quantities required to perform the subsequent physico-chemical and biochemical studies.
ISSN:0027-1314
1935-0260
DOI:10.3103/S0027131419060087