A Review on Domino Condensation/Cyclization Reactions for the Synthesis of 2‐Substituted 1,3‐Benzothiazole Derivatives

Domino reactions serve as one of the most step‐economical methods for the synthesis of benzoxazole molecules such as 2‐substituted 1,3‐benzothiazoles. Recently, a variety of compounds were found to facilitate these domino reactions. Here, we have summarized the most important domino condensation and cyclization reactions in view of the formation of 2‐substituted 1,3‐benzothiazoles using specific cyclization agents. This Minireview discusses the recent advances in the synthesis of 2‐substituted 1,3‐benzothiazoles using various carbonyl agents to facilitate cyclization.