Ethnicity and response to primary three‐dose hepatitis B vaccination in employees in the Netherlands, 1983 through 2017

Ethnicity and response to primary three‐dose hepatitis B vaccination in employees in the Netherlands, 1983 through 2017

Background and Aims Hepatitis B virus (HBV) vaccination is recommended to all employees who have an occupational risk in the Netherlands. This study assessed the determinants of the immune response to primary standard three‐dose HBV vaccination (0, 1, 6 months), with the main focus on ethnicity. Met...

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Veröffentlicht in:Journal of medical virology 2020-03, Vol.92 (3), p.309-316
Hauptverfasser: Koc, Özgür M., Menart, Charlotte, Theodore, Jemimah, Kremer, Cécile, Hens, Niel, Koek, Ger H, Oude Lashof, Astrid M. L.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Age
Confidence intervals
determinant
Ethnic Groups
Ethnicity
Female
Gender
Health risk assessment
healthcare workers
Hepatitis
Hepatitis B
Hepatitis B - immunology
Hepatitis B - prevention & control
Hepatitis B Antibodies - blood
Hepatitis B surface antigen
Hepatitis B Vaccines - administration & dosage
Hepatitis B Vaccines - immunology
Humans
Immune response
Immune system
Immunization Schedule
Immunogenicity
Logistic Models
Male
Males
Minority & ethnic groups
Netherlands - epidemiology
nonresponse
Population studies
Retrospective Studies
Schedules
Statistical analysis
Vaccination
Vaccines
Virology
Viruses
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Beschreibung
Zusammenfassung:Background and Aims Hepatitis B virus (HBV) vaccination is recommended to all employees who have an occupational risk in the Netherlands. This study assessed the determinants of the immune response to primary standard three‐dose HBV vaccination (0, 1, 6 months), with the main focus on ethnicity. Methods Out of 76 239 individuals who received HBV vaccination between April 1983 and December 2017, 11 567 persons with a known country of birth and complete vaccination schedule were included in this study. Weighted multiple logistic regression with Firth's bias adjustment was used to assess the determinants of nonresponse (anti‐HBs
ISSN:0146-6615
1096-9071
DOI:10.1002/jmv.25610