No Crossover Reactions to Citalopram or Paroxetine among Patients Hypersensitive to Zimeldine

Five patients who reacted with the hypersensitive syndrome to zimeldine showed no reaction to one of two other selective 5-HT reuptake inhibitors, citalopram or paroxetine. This further strengthens the impression that the mechanism for the hypersensitivity syndrome induced by zimeldine does not seem...

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Veröffentlicht in:	British journal of psychiatry 1991-06, Vol.158 (6), p.853-855
Hauptverfasser:	Bengtsson, Bengt-O., Lundmark, Jöns, Wålinder, Jan
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Antidepressants Antidepressive Agents Brief Reports Citalopram Citalopram - adverse effects Citalopram - therapeutic use Combined Modality Therapy Depressive Disorder - drug therapy Depressive Disorder - psychology Drug Hypersensitivity - diagnosis Drug Hypersensitivity - etiology Drug therapy Female Follow-Up Studies Humans Liver Function Tests Male Paroxetine Piperidines - adverse effects Piperidines - therapeutic use Serotonin Antagonists Zimeldine Zimeldine - adverse effects Zimeldine - therapeutic use
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Zusammenfassung:	Five patients who reacted with the hypersensitive syndrome to zimeldine showed no reaction to one of two other selective 5-HT reuptake inhibitors, citalopram or paroxetine. This further strengthens the impression that the mechanism for the hypersensitivity syndrome induced by zimeldine does not seem to be related primarily to the 5-HT reuptake inhibition as such.
ISSN:	0007-1250 1472-1465
DOI:	10.1192/bjp.158.6.853