Evaluation of Long Term Prognosis in Patients Treated with Narrowband Ultraviolet B: A Retrospective Study for 8 Years

Objective: Narrow-band ultraviolet B (NB-UVB) is a proven treatment modality in the management of psoriasis, inflammatory skin diseases and pigmentation disorders. However, recurrence is an important problem both for the patient and the clinician. The long-term effects of narrow-band ultraviolet B treatment on different dermatological indications cause concern. The aim of this study is to evaluate the effectiveness and the recurrence rates of the NB-UVB treatment in several dermatological diseases. Material and Methods: A total of 126 patients aged 18 years or older who received narrow-band ultraviolet B treatment due to various indications were included in the study. Treatment response and recurrence rates were retrospectively evaluated and compared in different disease groups. In addition, a statistical comparison was made between the recurrent and non-recurrent groups in terms of some variables that might affect relapse. Results: Complete remission, partial remission and unresponsiveness were detected in 74.6%, 13.5% and 11.9% of the patients respectively. The mean follow up period was 27.3±23.8 months. Recurrence was observed in 46.8% of patients with complete remission. Of the patients who developed recurrence, 59.1% had psoriasis, 13.6% mycosis fungoides, 13.6% atopic dermatitis, 6.8% vitiligo and 6.8% idiopathic pruritus. Conclusion: Based on our study findings, narrow-band ultraviolet B treatment may reduce the relapse rate in all dermatoses when scheduled in the early period. In addition to its widespread use in the treatment of psoriasis, it would be beneficial to consider narrow-band ultraviolet B as an effective treatment method in patients with idiopathic pruritus in the long-term period.