PGE2 hyperpolarizes gallbladder neurons and inhibits synaptic potentials in gallbladder ganglia

PGE2 hyperpolarizes gallbladder neurons and inhibits synaptic potentials in gallbladder ganglia

Gallbladder prostaglandin E2 (PGE2) levels are significantly elevated in pathophysiological conditions, resulting in changes in gallbladder motility or secretion that may involve actions of the prostanoid in intramural ganglia. This study was undertaken to examine the effects of PGE2 on neurons of t...

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Veröffentlicht in:American journal of physiology: Gastrointestinal and liver physiology 1998-03, Vol.37 (3), p.G493-G502
Hauptverfasser: JENNINGS, L. J, MAWE, G. M
Format: Artikel
Sprache:eng
Schlagworte:
Anatomy & physiology
Biological and medical sciences
Fundamental and applied biological sciences. Psychology
Gallbladder
Liver. Bile. Biliary tracts
Neurology
Vertebrates: digestive system
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Zusammenfassung:Gallbladder prostaglandin E2 (PGE2) levels are significantly elevated in pathophysiological conditions, resulting in changes in gallbladder motility or secretion that may involve actions of the prostanoid in intramural ganglia. This study was undertaken to examine the effects of PGE2 on neurons of the intramural ganglia of the guinea pig gallbladder.
ISSN:0193-1857
1522-1547