Polyamines are required for microtubule formation during gastric mucosal healing

Polyamines are required for microtubule formation during gastric mucosal healing

Polyamines are essential for the repair of gastric and duodenal erosions. Concentrated NaCl (3.4 M) given intragastrically damages the oxyntic gland mucosa and increases the activity of gastric mucosal ornithine decarboxylase (ODC), the first rate-limiting enzyme in polyamine synthesis, The nature o...

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Veröffentlicht in:American journal of physiology: Gastrointestinal and liver physiology 1998-05, Vol.37 (5), p.G879-G885
Hauptverfasser: BANAN, A, MCCORMACK, S. A, JOHNSON, L. R
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Enzymes
Fundamental and applied biological sciences. Psychology
Mucous membrane
Polymers
Stomach
Ulcers
Vertebrates: digestive system
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Zusammenfassung:Polyamines are essential for the repair of gastric and duodenal erosions. Concentrated NaCl (3.4 M) given intragastrically damages the oxyntic gland mucosa and increases the activity of gastric mucosal ornithine decarboxylase (ODC), the first rate-limiting enzyme in polyamine synthesis, The nature of the process of restitution of damaged mucosa is not well known, except that cell migration and the actin cytoskeleton play a prominent role.
ISSN:0193-1857
1522-1547