Transplanted hepatocytes proliferate differently after CCl4 treatment and hepatocyte growth factor infusion

Transplanted hepatocytes proliferate differently after CCl4 treatment and hepatocyte growth factor infusion

To understand regulation of transplanted hepatocyte proliferation in the normal liver, we used genetically marked rat or mouse cells. Hosts were subjected to liver injury by carbon tetrachloride (CCl4), to liver regeneration by a two-thirds partial hepatectomy, and to hepatocellular DNA synthesis by...

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Veröffentlicht in:American journal of physiology: Gastrointestinal and liver physiology 1999-03, Vol.39 (3), p.G629-G638
Hauptverfasser: GUPTA, S, RAJVANSHI, P, ARAGONA, E, LEE, C.-D, YERNENI, P. R, BURK, R. D
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Cell cycle, cell proliferation
Cell physiology
Cells
Fundamental and applied biological sciences. Psychology
Genetics
Liver
Molecular and cellular biology
Transplants & implants
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Zusammenfassung:To understand regulation of transplanted hepatocyte proliferation in the normal liver, we used genetically marked rat or mouse cells. Hosts were subjected to liver injury by carbon tetrachloride (CCl4), to liver regeneration by a two-thirds partial hepatectomy, and to hepatocellular DNA synthesis by infusion of hepatocyte growth factor for comparative analysis.
ISSN:0193-1857
1522-1547