Epithelial injury induces Egr-1 and Fos expression by a pathway involving protein kinase C and ERK

The signaling pathways activated in response to gastrointestinal injury remain poorly understood. Previous work has implicated the extracellular signal-regulated kinase (ERK) mitogen-activated protein kinase as a mediator of wound-signal transduction and a possible regulator of epithelial restitutio...

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Veröffentlicht in:American journal of physiology: Gastrointestinal and liver physiology 1999-02, Vol.39 (2), p.G322-G330
Hauptverfasser: DIECKGRAEFE, B. K, WEEMS, D. M
Format: Artikel
Sprache:eng
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Zusammenfassung:The signaling pathways activated in response to gastrointestinal injury remain poorly understood. Previous work has implicated the extracellular signal-regulated kinase (ERK) mitogen-activated protein kinase as a mediator of wound-signal transduction and a possible regulator of epithelial restitution.
ISSN:0193-1857
1522-1547