Transforming growth factor-β inhibits proliferation and maturation of cultured guinea pig gastric pit cells

We studied the effects of transforming growth factor-Beta1 (TGF-Beta1) on guinea pig gastric mucous cells, cultured in serum-free conditions. Electron microscopy showed that most cells were pre-pit cells, characterized by the presence of a few secretory granules scattered in the cytoplasm.

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Bibliographische Detailangaben
Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 1998-09, Vol.38 (3), p.G526-G533
Hauptverfasser:	ROKUTAN, K, YAMADA, M, TORIGOE, J, SAITO, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biological and medical sciences Cell physiology Cells Cellular biology Digestive system Fundamental and applied biological sciences. Psychology Molecular and cellular biology Responses to growth factors, tumor promotors, other factors Rodents
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Beschreibung
Zusammenfassung:	We studied the effects of transforming growth factor-Beta1 (TGF-Beta1) on guinea pig gastric mucous cells, cultured in serum-free conditions. Electron microscopy showed that most cells were pre-pit cells, characterized by the presence of a few secretory granules scattered in the cytoplasm.
ISSN:	0193-1857 1522-1547