Peripheral and central actions of orphanin FQ (nociceptin) on murine colon

Peripheral and central actions of orphanin FQ (nociceptin) on murine colon

Orphanin FQ (OFQ), also known as nociceptin, is a recently isolated endogenous peptide with a structure similar to the endogenous opiod peptides. The present study examined the actions of centrally administered OFQ on in vivo murine gastrointestinal and colonin transit as well as the actions of OFQ...

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Veröffentlicht in:American journal of physiology: Gastrointestinal and liver physiology 1999, Vol.39 (1), p.G125-G131
Hauptverfasser: OSINSKI, M. A, BASS, P, GAUMNITZ, E. A
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Colon
Digestive system
Fundamental and applied biological sciences. Psychology
Intestine. Mesentery
Nervous system
Peptides
Vertebrates: digestive system
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Zusammenfassung:Orphanin FQ (OFQ), also known as nociceptin, is a recently isolated endogenous peptide with a structure similar to the endogenous opiod peptides. The present study examined the actions of centrally administered OFQ on in vivo murine gastrointestinal and colonin transit as well as the actions of OFQ on the isolated colon.
ISSN:0193-1857
1522-1547