MEK inhibits secretin release and pancreatic secretion : Roles of secretin-releasing peptide and somatostatin

We investigated the mechanism of action of methionine enkephalin (MEK) on HCl-stimulated secretin release and pancreatic exocrine secretion. Anesthetized rats with pancreatobiliary cannulas and isolated upper small intestinal loops were perfused intraduodenally with 0.01 N HCl while bile and pancrea...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2001-05, Vol.43 (5), p.G890-G896
Hauptverfasser:	LI, James P, KAE YOL LEE, CHANG, Ta-Min, CHEY, William Y
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cellular biology Exocrine pancreas Fundamental and applied biological sciences. Psychology Pancreas Proteins Rodents Vertebrates: digestive system
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	We investigated the mechanism of action of methionine enkephalin (MEK) on HCl-stimulated secretin release and pancreatic exocrine secretion. Anesthetized rats with pancreatobiliary cannulas and isolated upper small intestinal loops were perfused intraduodenally with 0.01 N HCl while bile and pancreatic juice were diverted.
ISSN:	0193-1857 1522-1547