IL-2-deficient mice raised under germfree conditions develop delayed mild focal intestinal inflammation

Interleukin-2 (IL-1) amplifies immune stimuli and influences B cell differentiation. IL-2-deficient mice spontaneously develop intestinal inflammation if raised under specific pathogen-free (SPF) conditions.

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Bibliographische Detailangaben
Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 1999-06, Vol.39 (6), p.G1461-G1472
Hauptverfasser:	SCHULTZ, M, TONKONOGY, S. L, SELLON, R. K, VELTKAMP, C, GODFREY, V. L, KWON, J, GRENTHER, W. B, BALISH, E, HORAK, I, SARTOR, R. B
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria Biological and medical sciences Cellular biology Digestive system Gastroenterology. Liver. Pancreas. Abdomen Medical sciences Other diseases. Semiology Rodents Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
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Beschreibung
Zusammenfassung:	Interleukin-2 (IL-1) amplifies immune stimuli and influences B cell differentiation. IL-2-deficient mice spontaneously develop intestinal inflammation if raised under specific pathogen-free (SPF) conditions.
ISSN:	0193-1857 1522-1547