Alcoholic pancreatitis in rats: injury from nonoxidative metabolites of ethanol

Recent investigations suggest a role for fatty acid ethyl ester (FAEE), a nonoxidative metabolite for ethanol, in the pathogenesis of alcohol pancreatitis. Werner et al characterized ethanol-induced injury in rats and evaluated the contribution of oxidative and nonoxidative ethanol metabolites in th...

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Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2002-07, Vol.46 (1), p.G65-G73
Hauptverfasser:	WERNER, Jens, SAGHIR, Mouris, WARSHAW, Andrew L, LEWANDROWSKI, Kent B, LAPOSATA, Michael, IOZZO, Renato V, CARTER, Edward A, SCHATZ, Richard J, FERNANDEZ-DEL CASTILLO, Carlos
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcoholism and acute alcohol poisoning Biological and medical sciences Ethanol Fatty acids Medical sciences Metabolism Pancreas Toxicology
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Beschreibung
Zusammenfassung:	Recent investigations suggest a role for fatty acid ethyl ester (FAEE), a nonoxidative metabolite for ethanol, in the pathogenesis of alcohol pancreatitis. Werner et al characterized ethanol-induced injury in rats and evaluated the contribution of oxidative and nonoxidative ethanol metabolites in this form of acute pancreatitis.
ISSN:	0193-1857 1522-1547