Characteristics of rodent intestinal mucin Muc3 and alterations in a mouse model of human cystic fibrosis

Human mucin MUC3 and rodent Muc3 are widely assumed to represent secretory mucins expressed in columnar and goblet cells of the intestine. Using a 3'-oligonucleotide probe and in situ hypridization, we observed expression of rat Muc3 mostly in columnar cells.

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Bibliographische Detailangaben
Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2001-06, Vol.43 (6), p.G1321-G1330
Hauptverfasser:	KHATRI, Ismat A, HO, Catherine, SPECIAN, Robert D, FORSTNER, Janet F
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cells Cystic fibrosis Gastroenterology. Liver. Pancreas. Abdomen Large intestine Liver. Biliary tract. Portal circulation. Exocrine pancreas Medical sciences Other diseases. Semiology Rodents Small intestine
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Beschreibung
Zusammenfassung:	Human mucin MUC3 and rodent Muc3 are widely assumed to represent secretory mucins expressed in columnar and goblet cells of the intestine. Using a 3'-oligonucleotide probe and in situ hypridization, we observed expression of rat Muc3 mostly in columnar cells.
ISSN:	0193-1857 1522-1547