Vagal inhibition in the antral region of guinea pig stomach

The effects of vagal stimulation in the presence of a muscarinic antagonist were examined on three distinct rhythmically active cells located in guinea pig antrum. The observations suggest that vagal inhibition of stomach movements does not alter pacemaker activity in the stomach; rather, it results...

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Veröffentlicht in:American journal of physiology: Gastrointestinal and liver physiology 2000-08, Vol.42 (2), p.G388-G399
Hauptverfasser: DICKENS, E. J, EDWARDS, F. R, HIRST, G. D. S
Format: Artikel
Sprache:eng
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Zusammenfassung:The effects of vagal stimulation in the presence of a muscarinic antagonist were examined on three distinct rhythmically active cells located in guinea pig antrum. The observations suggest that vagal inhibition of stomach movements does not alter pacemaker activity in the stomach; rather, it results from a change in the sensitivity of smooth muscle contractile proteins to Ca(2+).
ISSN:0193-1857
1522-1547