rHuKGF ameliorates symptoms in DSS and CD4+CD45RBHi T cell transfer mouse models of inflammatory bowel disease

There is an acute need for effetive therapy for inflammatory bowel disease IBD particularly at the level of repair of the damaged epithelium. We evaluated the efficacy of recombinant human keratinocyte growth factor (rHuKGF) in both the dextran sodium sulfate (DSS) and the CD4+CD45RBHi T cell transf...

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Veröffentlicht in:American journal of physiology: Gastrointestinal and liver physiology 2002-04, Vol.45 (4), p.G690-G701
Hauptverfasser: BYRNE, Fergus R, FARRELL, Catherine L, ZIEGLER, Thomas R, SENALDI, Giorgio, ARANDA, Richard, REX, Karen L, SCULLY, Sheila, BROWN, Heather L, FLORES, Silvia A, GU, Li H, DANILENKO, Dimitry M, LACEY, David L
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container_end_page G701
container_issue 4
container_start_page G690
container_title American journal of physiology: Gastrointestinal and liver physiology
container_volume 45
creator BYRNE, Fergus R
FARRELL, Catherine L
ZIEGLER, Thomas R
SENALDI, Giorgio
ARANDA, Richard
REX, Karen L
SCULLY, Sheila
BROWN, Heather L
FLORES, Silvia A
GU, Li H
DANILENKO, Dimitry M
LACEY, David L
description There is an acute need for effetive therapy for inflammatory bowel disease IBD particularly at the level of repair of the damaged epithelium. We evaluated the efficacy of recombinant human keratinocyte growth factor (rHuKGF) in both the dextran sodium sulfate (DSS) and the CD4+CD45RBHi T cell transfer models of IBD.
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identifier ISSN: 0193-1857
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1522-1547
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source American Physiological Society Paid; EZB-FREE-00999 freely available EZB journals
subjects Biological and medical sciences
Bowel disease
Digestive system
Excretory system
Medical sciences
Membranes
Pharmacology. Drug treatments
Rodents
Therapy
title rHuKGF ameliorates symptoms in DSS and CD4+CD45RBHi T cell transfer mouse models of inflammatory bowel disease
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