COX inhibition excites enteric nerves that affect motility, alkaline secretion, and permeability in rat duodenum
In anesthetized rats, the cyclooxygenase (COX) inhibitor indomethacin induces duodenal motility, increases duodenal mucosal alkaline secretion (DMAS), and evokes a transient increase in duodenal paracellular permeability (DPP). To examine whether enteric nerves influence these responses, the duodenu...
Gespeichert in:
| Veröffentlicht in: | American journal of physiology: Gastrointestinal and liver physiology 2001-11, Vol.44 (5), p.G1169-G1178 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | G1178 |
|---|---|
| container_issue | 5 |
| container_start_page | G1169 |
| container_title | American journal of physiology: Gastrointestinal and liver physiology |
| container_volume | 44 |
| creator | NYLANDER, Olof HALLGREN, Anneli SABABI, Manaf |
| description | In anesthetized rats, the cyclooxygenase (COX) inhibitor indomethacin induces duodenal motility, increases duodenal mucosal alkaline secretion (DMAS), and evokes a transient increase in duodenal paracellular permeability (DPP). To examine whether enteric nerves influence these responses, the duodenum was perfused with lidocaine. |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pasca</sourceid><recordid>TN_cdi_proquest_journals_232580066</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>90810847</sourcerecordid><originalsourceid>FETCH-LOGICAL-p576-99396924f5aa38b2cca5ce964ae46786ba1ccd479e07de9ca3962366a980a6c03</originalsourceid><addsrcrecordid>eNotjU1LxDAYhIMouK7-hyB4s5CPJm2OsvgFC3vZg7fyNn3LZm3TmqTi_nvjx2mY4ZmZM7LiSoiCq7I6JyvGjSx4rapLchXjkTGmBOcrMm92b9T5g2tdcpOn-GVdwkjRJwzOUo_hM9t0gESh79EmOk7JDS6d7ikM7zA4jzSiDfjTz5nv6IxhRGh_qTxOQy53y9ShX8ZrctHDEPHmX9dk__S437wU293z6-ZhW8yq0oUx0mgjyl4ByLoV1oKyaHQJWOqq1i1wa7uyMsiqDo2FjAupNZiagbZMrsnt3-wcpo8FY2qO0xJ8fmyEFKpmTOsM3f1DEC0MfQBvXWzm4EYIp4aXXHBTa_kNdBNkcw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>232580066</pqid></control><display><type>article</type><title>COX inhibition excites enteric nerves that affect motility, alkaline secretion, and permeability in rat duodenum</title><source>American Physiological Society</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>NYLANDER, Olof ; HALLGREN, Anneli ; SABABI, Manaf</creator><creatorcontrib>NYLANDER, Olof ; HALLGREN, Anneli ; SABABI, Manaf</creatorcontrib><description>In anesthetized rats, the cyclooxygenase (COX) inhibitor indomethacin induces duodenal motility, increases duodenal mucosal alkaline secretion (DMAS), and evokes a transient increase in duodenal paracellular permeability (DPP). To examine whether enteric nerves influence these responses, the duodenum was perfused with lidocaine.</description><identifier>ISSN: 0193-1857</identifier><identifier>EISSN: 1522-1547</identifier><identifier>CODEN: APGPDF</identifier><language>eng</language><publisher>Bethesda, MD: American Physiological Society</publisher><subject>Anesthetics. Neuromuscular blocking agents ; Biochemistry ; Biological and medical sciences ; Digestive system ; Fundamental and applied biological sciences. Psychology ; Intestine. Mesentery ; Medical sciences ; Neurons ; Neuropharmacology ; Pharmacology. Drug treatments ; Rodents ; Vertebrates: digestive system</subject><ispartof>American journal of physiology: Gastrointestinal and liver physiology, 2001-11, Vol.44 (5), p.G1169-G1178</ispartof><rights>2002 INIST-CNRS</rights><rights>Copyright American Physiological Society Nov 2001</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=14121986$$DView record in Pascal Francis$$Hfree_for_read</backlink></links><search><creatorcontrib>NYLANDER, Olof</creatorcontrib><creatorcontrib>HALLGREN, Anneli</creatorcontrib><creatorcontrib>SABABI, Manaf</creatorcontrib><title>COX inhibition excites enteric nerves that affect motility, alkaline secretion, and permeability in rat duodenum</title><title>American journal of physiology: Gastrointestinal and liver physiology</title><description>In anesthetized rats, the cyclooxygenase (COX) inhibitor indomethacin induces duodenal motility, increases duodenal mucosal alkaline secretion (DMAS), and evokes a transient increase in duodenal paracellular permeability (DPP). To examine whether enteric nerves influence these responses, the duodenum was perfused with lidocaine.</description><subject>Anesthetics. Neuromuscular blocking agents</subject><subject>Biochemistry</subject><subject>Biological and medical sciences</subject><subject>Digestive system</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Intestine. Mesentery</subject><subject>Medical sciences</subject><subject>Neurons</subject><subject>Neuropharmacology</subject><subject>Pharmacology. Drug treatments</subject><subject>Rodents</subject><subject>Vertebrates: digestive system</subject><issn>0193-1857</issn><issn>1522-1547</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><recordid>eNotjU1LxDAYhIMouK7-hyB4s5CPJm2OsvgFC3vZg7fyNn3LZm3TmqTi_nvjx2mY4ZmZM7LiSoiCq7I6JyvGjSx4rapLchXjkTGmBOcrMm92b9T5g2tdcpOn-GVdwkjRJwzOUo_hM9t0gESh79EmOk7JDS6d7ikM7zA4jzSiDfjTz5nv6IxhRGh_qTxOQy53y9ShX8ZrctHDEPHmX9dk__S437wU293z6-ZhW8yq0oUx0mgjyl4ByLoV1oKyaHQJWOqq1i1wa7uyMsiqDo2FjAupNZiagbZMrsnt3-wcpo8FY2qO0xJ8fmyEFKpmTOsM3f1DEC0MfQBvXWzm4EYIp4aXXHBTa_kNdBNkcw</recordid><startdate>20011101</startdate><enddate>20011101</enddate><creator>NYLANDER, Olof</creator><creator>HALLGREN, Anneli</creator><creator>SABABI, Manaf</creator><general>American Physiological Society</general><scope>IQODW</scope></search><sort><creationdate>20011101</creationdate><title>COX inhibition excites enteric nerves that affect motility, alkaline secretion, and permeability in rat duodenum</title><author>NYLANDER, Olof ; HALLGREN, Anneli ; SABABI, Manaf</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p576-99396924f5aa38b2cca5ce964ae46786ba1ccd479e07de9ca3962366a980a6c03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Anesthetics. Neuromuscular blocking agents</topic><topic>Biochemistry</topic><topic>Biological and medical sciences</topic><topic>Digestive system</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Intestine. Mesentery</topic><topic>Medical sciences</topic><topic>Neurons</topic><topic>Neuropharmacology</topic><topic>Pharmacology. Drug treatments</topic><topic>Rodents</topic><topic>Vertebrates: digestive system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>NYLANDER, Olof</creatorcontrib><creatorcontrib>HALLGREN, Anneli</creatorcontrib><creatorcontrib>SABABI, Manaf</creatorcontrib><collection>Pascal-Francis</collection><jtitle>American journal of physiology: Gastrointestinal and liver physiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>NYLANDER, Olof</au><au>HALLGREN, Anneli</au><au>SABABI, Manaf</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>COX inhibition excites enteric nerves that affect motility, alkaline secretion, and permeability in rat duodenum</atitle><jtitle>American journal of physiology: Gastrointestinal and liver physiology</jtitle><date>2001-11-01</date><risdate>2001</risdate><volume>44</volume><issue>5</issue><spage>G1169</spage><epage>G1178</epage><pages>G1169-G1178</pages><issn>0193-1857</issn><eissn>1522-1547</eissn><coden>APGPDF</coden><abstract>In anesthetized rats, the cyclooxygenase (COX) inhibitor indomethacin induces duodenal motility, increases duodenal mucosal alkaline secretion (DMAS), and evokes a transient increase in duodenal paracellular permeability (DPP). To examine whether enteric nerves influence these responses, the duodenum was perfused with lidocaine.</abstract><cop>Bethesda, MD</cop><pub>American Physiological Society</pub></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0193-1857 |
| ispartof | American journal of physiology: Gastrointestinal and liver physiology, 2001-11, Vol.44 (5), p.G1169-G1178 |
| issn | 0193-1857 1522-1547 |
| language | eng |
| recordid | cdi_proquest_journals_232580066 |
| source | American Physiological Society; EZB-FREE-00999 freely available EZB journals |
| subjects | Anesthetics. Neuromuscular blocking agents Biochemistry Biological and medical sciences Digestive system Fundamental and applied biological sciences. Psychology Intestine. Mesentery Medical sciences Neurons Neuropharmacology Pharmacology. Drug treatments Rodents Vertebrates: digestive system |
| title | COX inhibition excites enteric nerves that affect motility, alkaline secretion, and permeability in rat duodenum |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T12%3A11%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pasca&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=COX%20inhibition%20excites%20enteric%20nerves%20that%20affect%20motility,%20alkaline%20secretion,%20and%20permeability%20in%20rat%20duodenum&rft.jtitle=American%20journal%20of%20physiology:%20Gastrointestinal%20and%20liver%20physiology&rft.au=NYLANDER,%20Olof&rft.date=2001-11-01&rft.volume=44&rft.issue=5&rft.spage=G1169&rft.epage=G1178&rft.pages=G1169-G1178&rft.issn=0193-1857&rft.eissn=1522-1547&rft.coden=APGPDF&rft_id=info:doi/&rft_dat=%3Cproquest_pasca%3E90810847%3C/proquest_pasca%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=232580066&rft_id=info:pmid/&rfr_iscdi=true |