Regulation of oligopeptide transporter (Pept-1) in experimental diabetes

The knowledge of expression and biology of the intestinal oligopeptide transporter (Pept-1) in a metabolic disorder such as diabetes may have nutritional and pharmacological implications. To study this problem, rats were made diabetic by streptozotocin injection, and Western and Northern blot analys...

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Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2002-07, Vol.46 (1), p.G133-G138
Hauptverfasser:	GANGOPADHYAY, Archana, THAMOTHARAN, Manikkavasagar, ADIBI, Siamak A
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Diabetes Diabetes. Impaired glucose tolerance Digestive system Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Genes Medical sciences Membranes Peptides
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	The knowledge of expression and biology of the intestinal oligopeptide transporter (Pept-1) in a metabolic disorder such as diabetes may have nutritional and pharmacological implications. To study this problem, rats were made diabetic by streptozotocin injection, and Western and Northern blot analyses and nuclear run-on assay were used to determine the protein and gene expression of Pept-1 and its rate of transcription, respectively.
ISSN:	0193-1857 1522-1547