Association of estrogen receptor a gene polymorphisms with neurofibrillary tangles

Estrogen receptor [alpha] (ER[alpha]) may be implicated in the pathogenesis of Alzheimer's disease (AD). The aim of this study was to clarify the association between ER[alpha] gene polymorphisms and AD-related pathologic changes. The staging of neurofibrillary tangles (NFT) and senile plaques (...

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Veröffentlicht in:	Dementia and geriatric cognitive disorders 2004, Vol.18 (2), p.145-150
Hauptverfasser:	KAZAMA, Hirohito, RUBERU, Nyoka N, ORIMO, Hajime, HOSOI, Takayuki, MURAYAMA, Shigeo, SAITO, Yuko, NAKAHARA, Ken-Ichi, KANEMARU, Kazutomi, NAGURA, Hiroshi, ARAI, Tomio, SAWABE, Motoji, YAMANOUCHI, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Medical sciences Neurology
Online-Zugang:	Volltext
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Zusammenfassung:	Estrogen receptor [alpha] (ER[alpha]) may be implicated in the pathogenesis of Alzheimer's disease (AD). The aim of this study was to clarify the association between ER[alpha] gene polymorphisms and AD-related pathologic changes. The staging of neurofibrillary tangles (NFT) and senile plaques (SP) was performed according to the method by Braak and Braak and two polymorphisms,
ISSN:	1420-8008 1421-9824