Is diuretic therapy associated with an increased risk of colon cancer?

Several studies have suggested that long-term diuretic therapy may be associated with an increased risk of renal cell carcinoma. Although renal cell carcinoma is uncommon, it may share risk factors with colon cancer, suggesting that the two malignancies may have similar carcinogenic mechanisms.

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Bibliographische Detailangaben
Veröffentlicht in:	The American journal of medicine 2001-02, Vol.110 (2), p.143-145
Hauptverfasser:	Tenenbaum, Alexander, Motro, Michael, Jonas, Michael, Fisman, Enrique Z, Grossman, Ehud, Boyko, Valentina, Behar, Solomon, Reicher-Reiss, Henrietta
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences Colonic Neoplasms - chemically induced Colonic Neoplasms - epidemiology Colorectal cancer Confounding Factors (Epidemiology) Diuretics Diuretics - adverse effects Drug toxicity and drugs side effects treatment Female Gastroenterology. Liver. Pancreas. Abdomen Health risk assessment Humans Incidence Male Medical sciences Middle Aged Multivariate Analysis Pharmacology. Drug treatments Proportional Hazards Models Risk Risk Factors Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Toxicity: digestive system Tropical medicine Tumors United States - epidemiology
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Beschreibung
Zusammenfassung:	Several studies have suggested that long-term diuretic therapy may be associated with an increased risk of renal cell carcinoma. Although renal cell carcinoma is uncommon, it may share risk factors with colon cancer, suggesting that the two malignancies may have similar carcinogenic mechanisms.
ISSN:	0002-9343 1555-7162
DOI:	10.1016/S0002-9343(00)00674-4