Severe and persistent hypoglycemia due to gatifloxacin interaction with oral hypoglycemic agents

Menzies et al report three cases of severe and persistent hypoglycemia due to gatifloxacin in adults with diabetes mellitus who were taking oral hypoglycemic agents. This phenomenon, which is not a quinolone class effect, has important clinical implications for diabetic patients who are also treated...

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Veröffentlicht in:	The American journal of medicine 2002-08, Vol.113 (3), p.232-234
Hauptverfasser:	MENZIES, Dhananjai J, DORSAINVIL, Pierre A, CUNHA, Burke A, JOHNSON, Diane H
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Aged Aged, 80 and over Anti-Infective Agents - administration & dosage Anti-Infective Agents - adverse effects Associated diseases and complications Bacterial Infections - drug therapy Biological and medical sciences Blood Glucose - drug effects Case studies Diabetes Diabetes Mellitus, Type 2 - diagnosis Diabetes Mellitus, Type 2 - drug therapy Diabetes. Impaired glucose tolerance Drug Interactions Drug therapy Endocrine pancreas. Apud cells (diseases) Endocrinopathies Female Fluoroquinolones Follow-Up Studies Gatifloxacin Humans Hypoglycemia - diagnosis Hypoglycemia - etiology Hypoglycemic Agents - administration & dosage Hypoglycemic Agents - adverse effects Male Medical sciences Miscellaneous Pharmacology. Drug treatments Risk Assessment Side effects
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Zusammenfassung:	Menzies et al report three cases of severe and persistent hypoglycemia due to gatifloxacin in adults with diabetes mellitus who were taking oral hypoglycemic agents. This phenomenon, which is not a quinolone class effect, has important clinical implications for diabetic patients who are also treated with gatifloxacin.
ISSN:	0002-9343 1555-7162
DOI:	10.1016/S0002-9343(02)01158-0