Differential regulation of leptin expression and function in A/J vs. C57BL/6J mice during diet-induced obesity

Differential regulation of leptin expression and function in A/J vs. C57BL/6J mice during diet-induced obesity

Obesity-resistant (A/J) and obesity-prone (C57BL/6J) mice were weaned onto low-fat (LF) or high-fat (HF) diets and studied after 2, 10, and 16 wk. Despite consuming the same amount of food, AM mice on the HF diet deposited less carcass lipid and gained less weight than C57BL/6J mice over the course...

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Veröffentlicht in:American journal of physiology: endocrinology and metabolism 2000-08, Vol.42 (2), p.E356-E365
Hauptverfasser: WATSON, P. M, COMMINS, S. P, BEILER, R. J, HATCHER, H. C, GETTYS, T. W
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Diet
Lipids
Medical sciences
Metabolic diseases
Obesity
Proteins
Rodents
Tissues
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Zusammenfassung:Obesity-resistant (A/J) and obesity-prone (C57BL/6J) mice were weaned onto low-fat (LF) or high-fat (HF) diets and studied after 2, 10, and 16 wk. Despite consuming the same amount of food, AM mice on the HF diet deposited less carcass lipid and gained less weight than C57BL/6J mice over the course of the study.
ISSN:0193-1849
1522-1555