Antioxidants reversibly inhibit the spontaneous resumption of meiosis

We previously showed that the cell-permeant antioxidant 2(3)-tert-butyl-4-hydroxyanisole (BHA) inhibited germinal vesicle breakdown (GVBD) in oocyte-cumulus complexes (OCC) of the rat. The objective of the present studies was to assess other antioxidants and whether such inhibition was reversible.

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Veröffentlicht in:American journal of physiology: endocrinology and metabolism 1999-04, Vol.39 (4), p.E684-E688
Hauptverfasser: TAKAMI, M, PRESTON, S. L, TOYLOY, V. A, BEHRMAN, H. R
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Sprache:eng
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Zusammenfassung:We previously showed that the cell-permeant antioxidant 2(3)-tert-butyl-4-hydroxyanisole (BHA) inhibited germinal vesicle breakdown (GVBD) in oocyte-cumulus complexes (OCC) of the rat. The objective of the present studies was to assess other antioxidants and whether such inhibition was reversible.
ISSN:0193-1849
1522-1555