In vivo measurement of fatty acids and cholesterol synthesis using D(2)O and mass isotopomer analysis

In vivo measurement of fatty acids and cholesterol synthesis using D(2)O and mass isotopomer analysis

The results of a study using Sprague-Dawley rats indicate that mass isotopomer distribution analysis and deuterated water can be used not only to quantitate the replacement rate of many lipids in various compartments but may also be used to elucidate the tissue-specific synthetic pathways from the m...

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Veröffentlicht in:American journal of physiology: endocrinology and metabolism 1994-05, Vol.29 (5), p.E699
Hauptverfasser: Lee, W N Paul, Bassilian, Sara, Ajie, Henry O, Schoeller, Dale A
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Sprache:eng
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Cholesterol
Lipids
Medical research
Metabolism
Rodents
Water
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creator Lee, W N Paul
Bassilian, Sara
Ajie, Henry O
Schoeller, Dale A
description The results of a study using Sprague-Dawley rats indicate that mass isotopomer distribution analysis and deuterated water can be used not only to quantitate the replacement rate of many lipids in various compartments but may also be used to elucidate the tissue-specific synthetic pathways from the maximum incorporation number.
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ispartof American journal of physiology: endocrinology and metabolism, 1994-05, Vol.29 (5), p.E699
issn 0193-1849
1522-1555
language eng
recordid cdi_proquest_journals_232326908
source Alma/SFX Local Collection
subjects Cholesterol
Lipids
Medical research
Metabolism
Rodents
Water
title In vivo measurement of fatty acids and cholesterol synthesis using D(2)O and mass isotopomer analysis
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