Effect of a glucokinase inhibitor on energy production and insulin release in pancreatic islets

The results of a study are consistent with a model in which the primary importance of glycolysis in transducing the glucose signal into changes of the phosphate imparts to glucokinase a high control strength on glucose-induced insulin secretion.

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Veröffentlicht in:American journal of physiology: endocrinology and metabolism 1996-09, Vol.34 (3), p.E606
Hauptverfasser: Sweet, Ian R, Li, Guizhu, Najafi, Habiba, Berner, Donna, Matschinsky, Franz M
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container_title American journal of physiology: endocrinology and metabolism
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creator Sweet, Ian R
Li, Guizhu
Najafi, Habiba
Berner, Donna
Matschinsky, Franz M
description The results of a study are consistent with a model in which the primary importance of glycolysis in transducing the glucose signal into changes of the phosphate imparts to glucokinase a high control strength on glucose-induced insulin secretion.
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identifier ISSN: 0193-1849
ispartof American journal of physiology: endocrinology and metabolism, 1996-09, Vol.34 (3), p.E606
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source Alma/SFX Local Collection
subjects Cellular biology
Insulin
Mathematical models
Pancreas
title Effect of a glucokinase inhibitor on energy production and insulin release in pancreatic islets
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