Regulation of skeletal muscle glycogen phosphorylase and PDH during maximal intermittent exercise

The time course for the activation of glycogen phosphorylase (Phos) and pyruvate dehydrogenase (PDH) and their allosteric regulators was determined in human skeletal muscle during repeated bouts of maximal exercise. Six subjects completed three 30-s bouts of maximal isokinetic cycling separated by 4...

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Veröffentlicht in:American journal of physiology: endocrinology and metabolism 1999-11, Vol.40 (5), p.E890-E900
Hauptverfasser: PAROLIN, M. L, CHESLEY, A, MATSOS, M. P, SPRIET, L. L, JONES, N. L, HEIGENHAUSER, G. J. F
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Sprache:eng
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Zusammenfassung:The time course for the activation of glycogen phosphorylase (Phos) and pyruvate dehydrogenase (PDH) and their allosteric regulators was determined in human skeletal muscle during repeated bouts of maximal exercise. Six subjects completed three 30-s bouts of maximal isokinetic cycling separated by 4-min recovery periods. Muscle biopsies were taken at rest and at 6, 15, and 30 s of exercise during bouts 1 and 3.
ISSN:0193-1849
1522-1555