Isotopomer spectral analysis of intermediates of cholesterol synthesis in human subjects and hepatic cells

Isotopomer spectral analysis of intermediates of cholesterol synthesis in human subjects and hepatic cells

Steroid intermediates of the cholesterol synthesis pathway are characterized by rapid turnover rates relative to cholesterol due to their small pool size. Because the small pools will label rapidly, these intermediates may provide valuable information about the incorporation of isotopes in de novo s...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:American journal of physiology: endocrinology and metabolism 2002-06, Vol.45 (6), p.E1222-E1230
Hauptverfasser: LINDENTHAL, B, ALDAGHLAS, T. A, HOLLERAN, A. L, SUDHOP, T, BERTHOLD, H. K, VON BERGMANN, K, KELLEHER, J. K
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Cells
Cholesterol
Fundamental and applied biological sciences. Psychology
Isotopes
Lipids. Glycolipids
Metabolisms and neurohumoral controls
Vertebrates: anatomy and physiology, studies on body, several organs or systems
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Steroid intermediates of the cholesterol synthesis pathway are characterized by rapid turnover rates relative to cholesterol due to their small pool size. Because the small pools will label rapidly, these intermediates may provide valuable information about the incorporation of isotopes in de novo synthesis of cholesterol and realted compounds .
ISSN:0193-1849
1522-1555