Methylation demand and homocysteine metabolism : effects of dietary provision of creatine and guanidinoacetate

S-adenosylmethionine, formed by the adenylation of methionine via S-adenosylmethionine synthase, is the methyl donor in virtually all known biological methylations. These methylation reactions produce a methylated substrate and S-adenosylhomocysteine, which is subsequently metabolized to homocystein...

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Veröffentlicht in:American journal of physiology: endocrinology and metabolism 2001-11, Vol.44 (5), p.E1095-E1100
Hauptverfasser: STEAD, Lori M, AU, Keegan P, JACOBS, René L, BROSNAN, Margaret E, BROSNAN, John T
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Sprache:eng
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Zusammenfassung:S-adenosylmethionine, formed by the adenylation of methionine via S-adenosylmethionine synthase, is the methyl donor in virtually all known biological methylations. These methylation reactions produce a methylated substrate and S-adenosylhomocysteine, which is subsequently metabolized to homocysteine.
ISSN:0193-1849
1522-1555