Insulin does not change the intracellular distribution of hexokinase in rat heart

Insulin does not change the intracellular distribution of hexokinase in rat heart

Preliminary evidence has suggested that hexokinase in rat heart changes its kinetic properties in response to insulin through translocation to the outer mitochondrial membrane. We reexamined this hypothesis in light of tracer kinetic evidence to the contrary.

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Veröffentlicht in:American journal of physiology: endocrinology and metabolism 1998-10, Vol.38 (4), p.E558-E567
Hauptverfasser: DOENST, T, QIUYING HAN, GOODWIN, G. W, GUTHRIE, P. H, TAEGTMEYER, H
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Fundamental and applied biological sciences. Psychology
Glucose
Heart
Insulin
Kinetics
Rodents
Vertebrates: cardiovascular system
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Zusammenfassung:Preliminary evidence has suggested that hexokinase in rat heart changes its kinetic properties in response to insulin through translocation to the outer mitochondrial membrane. We reexamined this hypothesis in light of tracer kinetic evidence to the contrary.
ISSN:0193-1849
1522-1555