Normal Akt/PKB with reduced PI3K activation in isulin-resistant mice
Insulin stimulates muscle and adipose tissue to absorb glucose through a signaling cascade that is incompletely understood. Insulin resistance, the inability of insulin to appropriately stimulate glucose uptake, is a hallmark of type 2 diabetes mellitus.
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Veröffentlicht in: | American journal of physiology: endocrinology and metabolism 2001-12, Vol.44 (6), p.E1249 |
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container_issue | 6 |
container_start_page | E1249 |
container_title | American journal of physiology: endocrinology and metabolism |
container_volume | 44 |
creator | Nadler, Samuel T Stoehr, Jonathan P Rabaglia, Mary E Schueler, Kathryn L |
description | Insulin stimulates muscle and adipose tissue to absorb glucose through a signaling cascade that is incompletely understood. Insulin resistance, the inability of insulin to appropriately stimulate glucose uptake, is a hallmark of type 2 diabetes mellitus. |
format | Article |
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identifier | ISSN: 0193-1849 |
ispartof | American journal of physiology: endocrinology and metabolism, 2001-12, Vol.44 (6), p.E1249 |
issn | 0193-1849 1522-1555 |
language | eng |
recordid | cdi_proquest_journals_232312264 |
source | American Physiological Society; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
subjects | Diabetes Enzymes Glucose Insulin Proteins |
title | Normal Akt/PKB with reduced PI3K activation in isulin-resistant mice |
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