Non-Hodgkin Lymphoma with Synovial Involvement of the Knee

Musculoskeletal involvement occurs in approximately 25% of patients diagnosed with non-Hodgkin lymphoma (NHL). Skeletal involvement is typically secondary with primary lymphoma of the bone being much rarer. We describe a case in which a 52-year-old man initially presented features suggestive of Lyme...

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Veröffentlicht in:Bulletin of the NYU Hospital for Joint Diseases 2019-10, Vol.77 (4), p.275-278
Hauptverfasser: Kim, Brandon, Raphael, Bruce, Liu, Cynthia, Golden, Brian D
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Sprache:eng
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Zusammenfassung:Musculoskeletal involvement occurs in approximately 25% of patients diagnosed with non-Hodgkin lymphoma (NHL). Skeletal involvement is typically secondary with primary lymphoma of the bone being much rarer. We describe a case in which a 52-year-old man initially presented features suggestive of Lyme arthritis in his left knee. A synovial biopsy performed as part of a synovectomy procedure revealed a proliferative synovium with dense lymphoplasmacytic B cell infiltrate, suggestive of NHL. An inguinal lymph node biopsy was also performed but did not produce results pathologically similar to those of the left knee synovial biopsy.
ISSN:1936-9719
1936-9727