Differential gene expression in a murine model of cancer cachexia

Murine adenocarcinoma 16 (MAC16) tumors and cell lines induce cachexia in NMRI nude mice, whereas histologically similar MAC13 tumors do not. After confirming these findings in BALB/c nude mice, we demonstrated that this tissue wasting was not related to decreased food intake or increased total body...

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Veröffentlicht in:	American journal of physiology: endocrinology and metabolism 2001-08, Vol.44 (2), p.E289-E297
Hauptverfasser:	MONITTO, Constance L, BERKOWITZ, Dan, KYOUNG MIN LEE, PIN, Sokhon, LI, Daqing, BRESLOW, Michael, O'MALLEY, Bert, SCHILLER, Martin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal tumors. Experimental tumors Biological and medical sciences Cancer Cells Deoxyribonucleic acid DNA Experimental tumors, general aspects Genes Medical sciences Metabolism Rodents Tumors
Online-Zugang:	Volltext
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Zusammenfassung:	Murine adenocarcinoma 16 (MAC16) tumors and cell lines induce cachexia in NMRI nude mice, whereas histologically similar MAC13 tumors do not. After confirming these findings in BALB/c nude mice, we demonstrated that this tissue wasting was not related to decreased food intake or increased total body oxidative metabolism.
ISSN:	0193-1849 1522-1555