Fe-N/C single-atom catalysts exhibiting multienzyme activity and ROS scavenging ability in cells

Fe-N/C single atom catalysts (SACs) exhibit peroxidase-like, oxidase-like, catalase-like, and glutathione peroxidase-like activity. Fe-N/C SACs are successfully applied to control the intracellular H 2 O 2 level. This study not only explores the types of SACs mimicking enzymes but also provides oppo...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2019-11, Vol.55 (96), p.14534-14537
Hauptverfasser:	Lu, Mingju, Wang, Chao, Ding, Yongqi, Peng, Meihong, Zhang, Wang, Li, Kai, Wei, Wei, Lin, Yuqing
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioengineering Biomimetic Materials - chemistry Biomimetic Materials - metabolism Biomimetic Materials - pharmacology Carbon - chemistry Catalase Catalase - chemistry Catalase - metabolism Catalysis Cell Survival - drug effects Glutathione Glutathione Peroxidase - chemistry Glutathione Peroxidase - metabolism HeLa Cells Humans Hydrogen peroxide Hydrogen Peroxide - chemistry Hydrogen Peroxide - metabolism Iron - chemistry Nitrogen - chemistry Oxidation-Reduction Peroxidase Porphyrins - chemistry Reactive Oxygen Species - chemistry Reactive Oxygen Species - metabolism Scavenging Single atom catalysts
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Zusammenfassung:	Fe-N/C single atom catalysts (SACs) exhibit peroxidase-like, oxidase-like, catalase-like, and glutathione peroxidase-like activity. Fe-N/C SACs are successfully applied to control the intracellular H 2 O 2 level. This study not only explores the types of SACs mimicking enzymes but also provides opportunities for SACs in biomedical and other bioengineering applications. Fe-N/C single atom catalysts (SACs) exhibit peroxidase-like, oxidase-like, catalase-like, and glutathione peroxidase-like activity.
ISSN:	1359-7345 1364-548X
DOI:	10.1039/c9cc07408b