Successful treatment of post‐transplant CMV meningoencephalitis with third‐party CMV virus‐specific T cells: Lessons learned
Cytomegalovirus encephalitis is a challenging life‐threatening complication following hematopoietic stem cell transplantation for which medical treatment is usually ineffective or toxic. However, in recent years, adoptive T‐cell therapy has been reported to provide a significant chance of cure for p...
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| Veröffentlicht in: | Pediatric transplantation 2019-12, Vol.23 (8), p.e13584-n/a |
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| container_issue | 8 |
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| container_title | Pediatric transplantation |
| container_volume | 23 |
| creator | Alonso, Laura Rudilla, Francesc Gimeno, Ramón Codinach, Margarita Blanco, Margarita Querol, Sergio Diaz de Heredia, Cristina |
| description | Cytomegalovirus encephalitis is a challenging life‐threatening complication following hematopoietic stem cell transplantation for which medical treatment is usually ineffective or toxic. However, in recent years, adoptive T‐cell therapy has been reported to provide a significant chance of cure for patients with viral infections. Herein, two cases of pediatric patients successfully treated with third‐party donor‐derived virus‐specific T cells for CMV meningoencephalitis are reported. |
| doi_str_mv | 10.1111/petr.13584 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1397-3142 |
| ispartof | Pediatric transplantation, 2019-12, Vol.23 (8), p.e13584-n/a |
| issn | 1397-3142 1399-3046 |
| language | eng |
| recordid | cdi_proquest_journals_2317808302 |
| source | Wiley-Blackwell Journals |
| subjects | CMV Cytomegalovirus Encephalitis hematopoietic stem cell transplant Hematopoietic stem cells Lymphocytes T Meningitis Meningoencephalitis Patients Stem cell transplantation Transplants & implants virus‐specific T cells |
| title | Successful treatment of post‐transplant CMV meningoencephalitis with third‐party CMV virus‐specific T cells: Lessons learned |
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