Frontispiece: Modular Synthesis of DOTA‐Metal‐Based PSMA‐Targeted Imaging Agents for MRI and PET of Prostate Cancer

Targeted molecular imaging agents (TMIAs) are emerging as important tools for diagnosing cancer and other diseases. In their Communication on page 13848 ff., H. F. Schmitthenner et al. describe a modular approach to TMIA synthesis by introducing a metal atom early on to form an imaging module for MR...

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Veröffentlicht in:Chemistry : a European journal 2019-11, Vol.25 (61), p.n/a
Hauptverfasser: Schmitthenner, Hans F., Dobson, Damien E., Jones, Kelsea G., Akporji, Nnamdi, Soika, Dana Q. M., Nastiuk, Kent L., Hornak, Joseph P.
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Sprache:eng
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Zusammenfassung:Targeted molecular imaging agents (TMIAs) are emerging as important tools for diagnosing cancer and other diseases. In their Communication on page 13848 ff., H. F. Schmitthenner et al. describe a modular approach to TMIA synthesis by introducing a metal atom early on to form an imaging module for MRI or PET. This is coupled with a targeting module in a convergent step to form a selective imaging agent for prostate cancer. By grasping a branch, the colorful toucan emulates the color‐matched TMIA by targeting and lighting up the location of a tree in the forest.
ISSN:0947-6539
1521-3765
DOI:10.1002/chem.201986162